Contraindicated (1)pentobarbital decreases levels of vandetanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Keep away from coadministration with powerful CYP3A4 inducers; these medication lessen publicity to vandetanib by nearly forty%.Should the buprenorphine dose is inadequate plus the CYP3A4 inducer cannot be dimin
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